Hypothyroidism: This condition occurs when the thyroid gland does not produce enough thyroid hormones. Symptoms of hypothyroidism may include fatigue, weight gain, cold intolerance, constipation, dry skin, hair loss, and depression. The most common cause of hypothyroidism is autoimmune thyroiditis, also known as Hashimoto's thyroiditis, where the immune system attacks the thyroid gland. Other causes include iodine deficiency, thyroid surgery, radiation therapy, certain medications, and congenital hypothyroidism (present at birth).